基础信息
| 中文名称 | α-熊果苷 |
|---|---|
| INCI 名称 | 4-Hydroxyphenyla-D-glucopyranoside |
| CAS 号 | 84380-01-8 |
| 分子式 | C12H16O7 |
| 分子量 | 272.25 |
| SMILES | C1=CC(=CC=C1O)O[C@@H]2[C@@H]([C@H]([C@@H]([C@H](O2)CO)O)O)O |
| 分子结构 | |
| 主要用途 | 抑制酪氨酸酶活性，阻断黑色素生成；清除自由基，减少细胞氧化损伤；减轻皮肤炎症。 |
| 适配成分 | α-熊果苷的配伍性较强，常与其他美白成分协同使用以增强效果；需注意，其与某些成分（如尼泊金甲酯）可能产生有害物质，需谨慎搭配 |
| 应用类型 | 乳、霜、水、液、面膜 |
| 注意事项 | 敏感肌、孕妇慎用 |
| 描述 | α-熊果苷（alpha-Arbutin）是一种美白成分，通过抑制酪氨酸酶活性减少黑色素生成，用于提亮肤色、淡化色斑。 |
| 应用 | 化妆品 |
人类代谢数据库（HMDB）
| 书目 | HMDB0029943 |
|---|---|
| 名称 | Arbutin |
| 描述 | 熊果苷存在于苹果中。梨叶中的葡萄糖苷 |
| 形态 | Solid |
| chemspider | 389765 |
| drugbank | DB11217 |
| foodb | FDB030911 |
| pubchem_compound | 440936 |
| chebi | 18305 |
| knapsack | C00002638 |
| kegg | C06186 |
| biocyc | HYDROQUINONE-O-BETA-D-GLUCOPYRANOSIDE |
| wikipedia | Arbutin |
| vmh_ | ARBT |
| 植物名称 | NCBl分类数据库 | 种 | 属 | 科 |
|---|---|---|---|---|
| Dendrophthoe falcata | NA | NA | Dendrophthoe | Loranthaceae |
| Centaurea solstitialis | 347529 | Centaurea solstitialis | Centaurea | Asteraceae |
| Xanthorrhoea resinosa | 49740 | Xanthorrhoea resinosa | Xanthorrhoea | Asphodelaceae |
| Salvia cyanescens | 1933716 | Salvia cyanescens | Salvia | Lamiaceae |
| Maackia tashiroi | 256641 | Maackia tashiroi | Maackia | Fabaceae |
| Ocimum pilosum | NA | NA | Ocimum | Lamiaceae |
| Trapa japonica | 363523 | Trapa japonica | Trapa | Lythraceae |
| Ambrosia hispida | NA | NA | Ambrosia | Asteraceae |
| Rhododendron ungerni | NA | NA | Rhododendron | Ericaceae |
| Dorstenia barteri | NA | NA | Dorstenia | Moraceae |
| Lagochilus leiacanthus | NA | NA | Lagochilus | Lamiaceae |
| Diospyros peregrina | NA | NA | Diospyros | Ebenaceae |
| Diospyros elliptifolia | NA | NA | Diospyros | Ebenaceae |
| Myroxylon peruiferum | 1231556 | Myroxylon peruiferum | Myroxylon | Fabaceae |
| Strychnos tricalysioides | 1040936 | Strychnos tricalysioides | Strychnos | Loganiaceae |
| Piptostigma fugax | NA | NA | Piptostigma | Annonaceae |
| Diospyros abyssinica | 413718 | Diospyros abyssinica | Diospyros | Ebenaceae |
| Chara ceratophylla | NA | NA | Chara | Characeae |
| Cratystylis conocephala | 125682 | Cratystylis conocephala | Cratystylis | Asteraceae |
| Beaucarnea recurvata | 39519 | Beaucarnea recurvata | Beaucarnea | Asparagaceae |
| Cosmos diversifolius | NA | NA | Cosmos | Asteraceae |
| Trichodesma incanum | 1421769 | Trichodesma incanum | Trichodesma | Boraginaceae |
| Selaginella tamariscina | 137178 | Selaginella tamariscina | Selaginella | Selaginellaceae |
| Rhododendron mucronatum | 401655 | Rhododendron mucronatum | Rhododendron | Ericaceae |
| Onobrychis viciifolia | 3882 | Onobrychis viciifolia | Onobrychis | Fabaceae |
| Lonicera tatarica var. morrowii | 447676 | Lonicera tatarica | Lonicera | Caprifoliaceae |
| Inga velutina | 486091 | Inga velutina | Inga | Fabaceae |
| Curcuma caesia | 508682 | Curcuma caesia | Curcuma | Zingiberaceae |
| Lycium chinense | 112883 | Lycium chinense | Lycium | Solanaceae |
| Turnera diffusa | 329212 | Turnera diffusa | Turnera | Passifloraceae |
| Cathormion altissimum | NA | NA | Cathormion | Fabaceae |
| Urochloa decumbens | 240449 | Urochloa decumbens | Urochloa | Poaceae |
| Rhododendron dauricum | 880079 | Rhododendron dauricum | Rhododendron | Ericaceae |
| Lycium barbarum | 112863 | Lycium barbarum | Lycium | Solanaceae |
| Lycopodium japonicum | 672196 | Lycopodium japonicum | Lycopodium | Lycopodiaceae |
| Erythrophleum couminga | NA | NA | Erythrophleum | Fabaceae |
| Agave xylonacantha | NA | NA | Agave | Asparagaceae |
| Stephania hernandifolia | 152366 | Stephania hernandifolia | Stephania | Menispermaceae |
| Calophyllum inophyllum | 158927 | Calophyllum inophyllum | Calophyllum | Calophyllaceae |
| Selaginella pulvinata | 672198 | Selaginella pulvinata | Selaginella | Selaginellaceae |
| Afrocarpus gracilior | 165205 | Afrocarpus gracilior | Afrocarpus | Podocarpaceae |
| Fallopia multiflora | 76025 | Fallopia multiflora | Fallopia | Polygonaceae |
| Erythrina pallida | NA | NA | Erythrina | Fabaceae |
| Anthemis cretica | 127978 | Anthemis cretica | Anthemis | Asteraceae |
| Nelumbo nucifera | 4432 | Nelumbo nucifera | Nelumbo | Nelumbonaceae |
| Dendrophthoe falcata | NA | NA | Dendrophthoe | Loranthaceae |
| Centaurea solstitialis | 347529 | Centaurea solstitialis | Centaurea | Asteraceae |
| Xanthorrhoea resinosa | 49740 | Xanthorrhoea resinosa | Xanthorrhoea | Asphodelaceae |
| Salvia cyanescens | 1933716 | Salvia cyanescens | Salvia | Lamiaceae |
| Maackia tashiroi | 256641 | Maackia tashiroi | Maackia | Fabaceae |
| Ocimum pilosum | NA | NA | Ocimum | Lamiaceae |
| Trapa japonica | 363523 | Trapa japonica | Trapa | Lythraceae |
| Ambrosia hispida | NA | NA | Ambrosia | Asteraceae |
| Rhododendron ungerni | NA | NA | Rhododendron | Ericaceae |
| Dorstenia barteri | NA | NA | Dorstenia | Moraceae |
| Lagochilus leiacanthus | NA | NA | Lagochilus | Lamiaceae |
| Diospyros peregrina | NA | NA | Diospyros | Ebenaceae |
| Diospyros elliptifolia | NA | NA | Diospyros | Ebenaceae |
| Myroxylon peruiferum | 1231556 | Myroxylon peruiferum | Myroxylon | Fabaceae |
| Strychnos tricalysioides | 1040936 | Strychnos tricalysioides | Strychnos | Loganiaceae |
| Piptostigma fugax | NA | NA | Piptostigma | Annonaceae |
| Diospyros abyssinica | 413718 | Diospyros abyssinica | Diospyros | Ebenaceae |
| Chara ceratophylla | NA | NA | Chara | Characeae |
| Cratystylis conocephala | 125682 | Cratystylis conocephala | Cratystylis | Asteraceae |
| Centaurea arenaria | 1486496 | Centaurea arenaria | Centaurea | Asteraceae |
| Beaucarnea recurvata | 39519 | Beaucarnea recurvata | Beaucarnea | Asparagaceae |
| Cosmos diversifolius | NA | NA | Cosmos | Asteraceae |
| Trichodesma incanum | 1421769 | Trichodesma incanum | Trichodesma | Boraginaceae |
| Selaginella tamariscina | 137178 | Selaginella tamariscina | Selaginella | Selaginellaceae |
| Rhododendron mucronatum | 401655 | Rhododendron mucronatum | Rhododendron | Ericaceae |
| Onobrychis viciifolia | 3882 | Onobrychis viciifolia | Onobrychis | Fabaceae |
| Scorzonera hispanica | 114289 | Scorzonera hispanica | Scorzonera | Asteraceae |
| Lonicera tatarica var. morrowii | 447676 | Lonicera tatarica | Lonicera | Caprifoliaceae |
| Eucalyptus australiana | NA | NA | Eucalyptus | Myrtaceae |
| Inga velutina | 486091 | Inga velutina | Inga | Fabaceae |
| Curcuma caesia | 508682 | Curcuma caesia | Curcuma | Zingiberaceae |
| Lycium chinense | 112883 | Lycium chinense | Lycium | Solanaceae |
| Gutenbergia cordifolia | 1671336 | Gutenbergia cordifolia | Gutenbergia | Asteraceae |
| Turnera diffusa | 329212 | Turnera diffusa | Turnera | Passifloraceae |
| Ulva conglobata | NA | NA | Ulva | Ulvaceae |
| Cathormion altissimum | NA | NA | Cathormion | Fabaceae |
| Urochloa decumbens | 240449 | Urochloa decumbens | Urochloa | Poaceae |
| Antiphiona pinnatisecta | 81504 | Antiphiona pinnatisecta | Antiphiona | Asteraceae |
| Rhododendron dauricum | 880079 | Rhododendron dauricum | Rhododendron | Ericaceae |
| Astragalus dissectus | NA | NA | Astragalus | Fabaceae |
| Garcinia subelliptica | 212238 | Garcinia subelliptica | Garcinia | Clusiaceae |
| Lycium barbarum | 112863 | Lycium barbarum | Lycium | Solanaceae |
| Lycopodium japonicum | 672196 | Lycopodium japonicum | Lycopodium | Lycopodiaceae |
| Erythrophleum couminga | NA | NA | Erythrophleum | Fabaceae |
| Agave xylonacantha | NA | NA | Agave | Asparagaceae |
| Phelline lucida | 92224 | Phelline lucida | Phelline | Phellinaceae |
| Lactuca serriola | 75943 | Lactuca serriola | Lactuca | Asteraceae |
| Asparagus officinalis | 4686 | Asparagus officinalis | Asparagus | Asparagaceae |
| Artocarpus altilis | 194251 | Artocarpus altilis | Artocarpus | Moraceae |
| Ocotea minarum | 881606 | Ocotea minarum | Ocotea | Lauraceae |
| Centaurea corcubionensis | 1436089 | Centaurea corcubionensis | Centaurea | Asteraceae |
| Stephania hernandifolia | 152366 | Stephania hernandifolia | Stephania | Menispermaceae |
| Calophyllum inophyllum | 158927 | Calophyllum inophyllum | Calophyllum | Calophyllaceae |
| Selaginella pulvinata | 672198 | Selaginella pulvinata | Selaginella | Selaginellaceae |
| Afrocarpus gracilior | 165205 | Afrocarpus gracilior | Afrocarpus | Podocarpaceae |
| Cryptocarya oblata | 1312790 | Cryptocarya oblata | Cryptocarya | Lauraceae |
| Fallopia multiflora | 76025 | Fallopia multiflora | Fallopia | Polygonaceae |
| Eriostemon fitzgeraldii | NA | NA | Eriostemon | Rutaceae |
| Erythrina pallida | NA | NA | Erythrina | Fabaceae |
| Pseudocyclosorus subochthodes | 1132564 | Pseudocyclosorus subochthodes | Pseudocyclosorus | Thelypteridaceae |
| Anthemis cretica | 127978 | Anthemis cretica | Anthemis | Asteraceae |
| Nelumbo nucifera | 4432 | Nelumbo nucifera | Nelumbo | Nelumbonaceae |
| Solenopsis punctaticeps | NA | NA | Solenopsis | Campanulaceae |
| Phyllodium pulchellum | 406422 | Phyllodium pulchellum | Phyllodium | Fabaceae |
| Enicosanthum cupulare | NA | NA | Enicosanthum | Annonaceae |
| Centaurea arenaria | 1486496 | Centaurea arenaria | Centaurea | Asteraceae |
| Scorzonera hispanica | 114289 | Scorzonera hispanica | Scorzonera | Asteraceae |
| Eucalyptus australiana | NA | NA | Eucalyptus | Myrtaceae |
| Mikania scandens | 102787 | Mikania scandens | Mikania | Asteraceae |
| Cotylelobium scabriusculum | 365534 | Cotylelobium scabriusculum | Cotylelobium | Dipterocarpaceae |
| Gutenbergia cordifolia | 1671336 | Gutenbergia cordifolia | Gutenbergia | Asteraceae |
| Ulva conglobata | NA | NA | Ulva | Ulvaceae |
| Antiphiona pinnatisecta | 81504 | Antiphiona pinnatisecta | Antiphiona | Asteraceae |
| Astragalus dissectus | NA | NA | Astragalus | Fabaceae |
| Garcinia subelliptica | 212238 | Garcinia subelliptica | Garcinia | Clusiaceae |
| Phelline lucida | 92224 | Phelline lucida | Phelline | Phellinaceae |
| Lactuca serriola | 75943 | Lactuca serriola | Lactuca | Asteraceae |
| Asparagus officinalis | 4686 | Asparagus officinalis | Asparagus | Asparagaceae |
| Artocarpus altilis | 194251 | Artocarpus altilis | Artocarpus | Moraceae |
| Ocotea minarum | 881606 | Ocotea minarum | Ocotea | Lauraceae |
| Centaurea corcubionensis | 1436089 | Centaurea corcubionensis | Centaurea | Asteraceae |
| Cryptocarya oblata | 1312790 | Cryptocarya oblata | Cryptocarya | Lauraceae |
| Eriostemon fitzgeraldii | NA | NA | Eriostemon | Rutaceae |
| Pseudocyclosorus subochthodes | 1132564 | Pseudocyclosorus subochthodes | Pseudocyclosorus | Thelypteridaceae |
| Solenopsis punctaticeps | NA | NA | Solenopsis | Campanulaceae |
| Phyllodium pulchellum | 406422 | Phyllodium pulchellum | Phyllodium | Fabaceae |
| Enicosanthum cupulare | NA | NA | Enicosanthum | Annonaceae |
| Mikania scandens | 102787 | Mikania scandens | Mikania | Asteraceae |
| Cotylelobium scabriusculum | 365534 | Cotylelobium scabriusculum | Cotylelobium | Dipterocarpaceae |
其它信息
| inci名称 | (2R,3S,4S,5R,6S)-2-(hydroxymethyl)-6-(4-hydroxyphenoxy)oxane-3,4,5-triol |
|---|---|
| Pubchemid | 440936 |
| 分子式 | C12H16O7 |
| 分子量 | 272.25 |
| 其它 | 熊果苷。497-76-7. 阿尔布托赛德。乌尔辛。乌瓦索尔。β熊果苷。对熊果苷。4-羟基苯基β-D-吡喃葡萄糖苷。对羟基苯基β-D-葡萄糖苷。仲裁。熊果苷。Arbutyne。4-羟基苯基-β-D-吡喃葡萄糖苷。对羟基苯基β-D-吡喃葡萄糖苷。氢醌-O-β-D-吡喃葡萄糖苷。对苯二酚β-D-吡喃葡萄糖苷。氢醌葡萄糖。氢醌-β-D-吡喃葡萄糖苷。对苯二酚O-β-D-吡喃葡萄糖苷。UNII-C5INA23HXF。C5INA23HXF。（2R，3S，4S，5R，6S）-2-（羟甲基）-6-（4-羟基苯氧基）恶烷-3,4,5-三醇。CCRIS 9273。（2R，3S，4S，5R，6S）-2-（羟甲基）-6-（4-羟基苯氧基）四氢-2H-吡喃-3,4,5-三醇。切比：18305。HSDB 7661。NSC 4036。NSC-4036。电子公告207-850-3。β-D-吡喃葡萄糖苷，4-羟基苯基。品牌0089673。4-羟基苯基-β-D-吡喃葡萄糖苷。chemble232202。DTXCID5020152.5-17-07-00110（贝尔斯坦手册参考）。b-D-吡喃葡萄糖苷，4-羟基苯基。MFCD00016915.β-D-吡喃葡萄糖苷，4-羟基苯基。厄西。熊果苷（市场）。熊果苷[集市]。埃里科林。（2R，3S，4S，5R，6S）-2-（羟甲基）-6-（4-氧化基苯氧基）恶烷-3,4,5-三醇。CAS-497-76-7。氢醌葡萄糖。氢醌|A-D-吡喃葡萄糖苷。SR-050000002157-熊果苷。NCGC00095599-01。HYDRO H.Spectrum_000786。对苯二酚-D-葡萄糖苷。SpecPlus_000314。熊果苷。熊果苷，>=98%。熊果苷。熊果苷。Prestwick3_001026。Spectrum2_000662。光谱3_001233。光谱4_001474。光谱5_000147。阿布汀[卫生组织]。bmse000365.熊果苷（Uva，对熊果苷）。熊果苷，分析标准品。方案36351。BSPBio_001211。BSPBio_002706。对苯二酚-β-D-葡萄糖苷。KBioGR_002047。KBioSS_001266。光谱300539.mls00227046。第K1c_006410。4-羟基苯基吡喃葡萄糖苷。SPBio_000723。BPBio1_001333。MEGxp0_001504。KBio1_001354。KBio2_001266。KBio2_003834。KBio2_006402。KBio3_002206。HMS2098M13。HMS3715M13。对羟基苯基β-D-葡萄糖苷。Tosowoong男士护肤助推器。HY-N0192。4-羟基苯基-β-吡喃葡萄糖苷。对苯二酚β-D-吡喃葡萄糖苷。Tox21_11509。Tox21_302428。BDBM50219502。CCG-38565。s2263.AKOS015965305。Tox21_11509_1。DB11217.KS-5252。SDCCGMLS-0066538.P001。（2R，3S，4S，5R，6S）-2-（羟甲基）-6-（4-羟基苯氧基）四氢吡喃-3,4,5-三醇。对羟基苯基β-D-吡喃葡萄糖苷。SMP1_000028。NCGC00166076-02。NCGC00166076-03。NCGC00166076-04。NCGC00166076-07。NCGC00166076-09。NCGC00255705-01。AC-1983。β-D-吡喃葡萄糖苷，4-羟基苯基。I（2）-D-吡喃葡萄糖苷，4-羟基苯基。SMR001233417。去雀斑美白面膜。Sooryehan纯美白精华液。ICEKING美白祛斑精华。A0522.AB00443586。对苯二酚。贝塔-D-吡喃葡萄糖苷。SW199492-2。C06186.4-羟基苯基b-D-吡喃葡萄糖苷，9CI，8CI。EN300-7388350。A827849.熊果苷，主要药物参考标准。ISAKNOX白色交响增亮乳液。Q416446.冰祛斑美白洁面乳。SR-050000002157-2。SR-050000002157-4。α-熊果苷；4-氢醌-α-D-吡喃葡萄糖苷。BRD-K08037784-001-12-6。熊果苷，欧洲药典（EP）参考标准。4E19B706-2013-4401-A1FC-a154数据42b4。（2S，3R，4S，5S，6R）-2-（4-羟基苯氧基）-6-甲醇四氢吡喃-3,4,5-三醇。7OQ |
| InChI | InChI=1S/C12H16O7/c13-5-8-9(15)10(16)11(17)12(19-8)18-7-3-1-6(14)2-4-7/h1-4,8-17H,5H2/t8-,9-,10+,11-,12-/m1/s1 |
| InChIKey | BJRNKVDFDLYUGJ-RMPHRYRLSA-N |
价格
| 名称 | cas号 | 克重 | 价格(￥CNY) | |
|---|---|---|---|---|
| 1 | 熊果苷Arbutin | 497-76-7 | 5G | 200 |
| 2 | 熊果苷Arbutin | 497-76-7 | 25G | 820 |
| 3 | α-熊果苷α-Arbutin | 84380-01-8 | 5g | 200 |
| 4 | α-熊果苷α-Arbutin | 84380-01-8 | 25g | 610 |